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GENETYX CORPORATION -mac software version 17.0.2
A) A region of tmPlsC, mLPCAT and mLPCAT2 containing conserved regions, i.e., AGPAT motifs 1 (green), 2 (magenta), 3 (blue), and 4 (orange), was used as a query for <t>GENETYX-MAC</t> software. The amino acid residues analyzed by mutagenesis in this study are indicated with red open squares. Asterisks represent conserved residues, and dots represent weakly similar residues. B) Schematic representations of the structures of tmPlsC, mLPCAT1, and mLPCAT2. Motifs 1– 4 are colored green, magenta, blue, and orange, respectively. We modeled mLPCAT1 (light green domain) and mLPCAT2 (light blue domain) based on the crystal structure data for tmPlsC (beige). C) Homology modeling of mLPCAT1 and mLPCAT2. Ribbon models of tmPlsC (used as the template), mLPCAT1, and mLPCAT2. Motifs 1–4 are highlighted as follow: motif 1, green; motif 2, magenta; motif 3, blue; motif 4, orange.
Mac Software Version 17.0.2, supplied by GENETYX CORPORATION, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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A) A region of tmPlsC, mLPCAT and mLPCAT2 containing conserved regions, i.e., AGPAT motifs 1 (green), 2 (magenta), 3 (blue), and 4 (orange), was used as a query for <t>GENETYX-MAC</t> software. The amino acid residues analyzed by mutagenesis in this study are indicated with red open squares. Asterisks represent conserved residues, and dots represent weakly similar residues. B) Schematic representations of the structures of tmPlsC, mLPCAT1, and mLPCAT2. Motifs 1– 4 are colored green, magenta, blue, and orange, respectively. We modeled mLPCAT1 (light green domain) and mLPCAT2 (light blue domain) based on the crystal structure data for tmPlsC (beige). C) Homology modeling of mLPCAT1 and mLPCAT2. Ribbon models of tmPlsC (used as the template), mLPCAT1, and mLPCAT2. Motifs 1–4 are highlighted as follow: motif 1, green; motif 2, magenta; motif 3, blue; motif 4, orange.
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A) A region of tmPlsC, mLPCAT and mLPCAT2 containing conserved regions, i.e., AGPAT motifs 1 (green), 2 (magenta), 3 (blue), and 4 (orange), was used as a query for <t>GENETYX-MAC</t> software. The amino acid residues analyzed by mutagenesis in this study are indicated with red open squares. Asterisks represent conserved residues, and dots represent weakly similar residues. B) Schematic representations of the structures of tmPlsC, mLPCAT1, and mLPCAT2. Motifs 1– 4 are colored green, magenta, blue, and orange, respectively. We modeled mLPCAT1 (light green domain) and mLPCAT2 (light blue domain) based on the crystal structure data for tmPlsC (beige). C) Homology modeling of mLPCAT1 and mLPCAT2. Ribbon models of tmPlsC (used as the template), mLPCAT1, and mLPCAT2. Motifs 1–4 are highlighted as follow: motif 1, green; motif 2, magenta; motif 3, blue; motif 4, orange.
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A) A region of tmPlsC, mLPCAT and mLPCAT2 containing conserved regions, i.e., AGPAT motifs 1 (green), 2 (magenta), 3 (blue), and 4 (orange), was used as a query for <t>GENETYX-MAC</t> software. The amino acid residues analyzed by mutagenesis in this study are indicated with red open squares. Asterisks represent conserved residues, and dots represent weakly similar residues. B) Schematic representations of the structures of tmPlsC, mLPCAT1, and mLPCAT2. Motifs 1– 4 are colored green, magenta, blue, and orange, respectively. We modeled mLPCAT1 (light green domain) and mLPCAT2 (light blue domain) based on the crystal structure data for tmPlsC (beige). C) Homology modeling of mLPCAT1 and mLPCAT2. Ribbon models of tmPlsC (used as the template), mLPCAT1, and mLPCAT2. Motifs 1–4 are highlighted as follow: motif 1, green; motif 2, magenta; motif 3, blue; motif 4, orange.
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Endress+Hauser inc image analyzer lab works software version 17.0
A) A region of tmPlsC, mLPCAT and mLPCAT2 containing conserved regions, i.e., AGPAT motifs 1 (green), 2 (magenta), 3 (blue), and 4 (orange), was used as a query for <t>GENETYX-MAC</t> software. The amino acid residues analyzed by mutagenesis in this study are indicated with red open squares. Asterisks represent conserved residues, and dots represent weakly similar residues. B) Schematic representations of the structures of tmPlsC, mLPCAT1, and mLPCAT2. Motifs 1– 4 are colored green, magenta, blue, and orange, respectively. We modeled mLPCAT1 (light green domain) and mLPCAT2 (light blue domain) based on the crystal structure data for tmPlsC (beige). C) Homology modeling of mLPCAT1 and mLPCAT2. Ribbon models of tmPlsC (used as the template), mLPCAT1, and mLPCAT2. Motifs 1–4 are highlighted as follow: motif 1, green; motif 2, magenta; motif 3, blue; motif 4, orange.
Image Analyzer Lab Works Software Version 17.0, supplied by Endress+Hauser inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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A) A region of tmPlsC, mLPCAT and mLPCAT2 containing conserved regions, i.e., AGPAT motifs 1 (green), 2 (magenta), 3 (blue), and 4 (orange), was used as a query for <t>GENETYX-MAC</t> software. The amino acid residues analyzed by mutagenesis in this study are indicated with red open squares. Asterisks represent conserved residues, and dots represent weakly similar residues. B) Schematic representations of the structures of tmPlsC, mLPCAT1, and mLPCAT2. Motifs 1– 4 are colored green, magenta, blue, and orange, respectively. We modeled mLPCAT1 (light green domain) and mLPCAT2 (light blue domain) based on the crystal structure data for tmPlsC (beige). C) Homology modeling of mLPCAT1 and mLPCAT2. Ribbon models of tmPlsC (used as the template), mLPCAT1, and mLPCAT2. Motifs 1–4 are highlighted as follow: motif 1, green; motif 2, magenta; motif 3, blue; motif 4, orange.
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Image Search Results


A) A region of tmPlsC, mLPCAT and mLPCAT2 containing conserved regions, i.e., AGPAT motifs 1 (green), 2 (magenta), 3 (blue), and 4 (orange), was used as a query for GENETYX-MAC software. The amino acid residues analyzed by mutagenesis in this study are indicated with red open squares. Asterisks represent conserved residues, and dots represent weakly similar residues. B) Schematic representations of the structures of tmPlsC, mLPCAT1, and mLPCAT2. Motifs 1– 4 are colored green, magenta, blue, and orange, respectively. We modeled mLPCAT1 (light green domain) and mLPCAT2 (light blue domain) based on the crystal structure data for tmPlsC (beige). C) Homology modeling of mLPCAT1 and mLPCAT2. Ribbon models of tmPlsC (used as the template), mLPCAT1, and mLPCAT2. Motifs 1–4 are highlighted as follow: motif 1, green; motif 2, magenta; motif 3, blue; motif 4, orange.

Journal: bioRxiv

Article Title: Mutagenesis and homology modeling reveal a predicted pocket of lysophosphatidylcholine acyltransferase 2 to catch Acyl-CoA

doi: 10.1101/2020.10.31.363515

Figure Lengend Snippet: A) A region of tmPlsC, mLPCAT and mLPCAT2 containing conserved regions, i.e., AGPAT motifs 1 (green), 2 (magenta), 3 (blue), and 4 (orange), was used as a query for GENETYX-MAC software. The amino acid residues analyzed by mutagenesis in this study are indicated with red open squares. Asterisks represent conserved residues, and dots represent weakly similar residues. B) Schematic representations of the structures of tmPlsC, mLPCAT1, and mLPCAT2. Motifs 1– 4 are colored green, magenta, blue, and orange, respectively. We modeled mLPCAT1 (light green domain) and mLPCAT2 (light blue domain) based on the crystal structure data for tmPlsC (beige). C) Homology modeling of mLPCAT1 and mLPCAT2. Ribbon models of tmPlsC (used as the template), mLPCAT1, and mLPCAT2. Motifs 1–4 are highlighted as follow: motif 1, green; motif 2, magenta; motif 3, blue; motif 4, orange.

Article Snippet: Sequence alignments were generated using GENETYX-MAC software version 17.0.2 (GENETYX Corporation).

Techniques: Software, Mutagenesis